Psoriatic Arthritis (PsA) is not a disease but an autoimmune disorder that occurs due to constant accumulation, expansion and localization of toxins. The disorder only appears when a trigger gets activated. 40% of psoriasis patients develop psoriatic arthritis and psoriatic arthritis is generally preceded by nail pitting.
• Abnormal immune response
• Family history of either psoriasis or psoriatic arthritis
Certain factors may trigger psoriasis, including:
• Emotional stress
• Environmental factors
• Physical trauma to skin
• Sun burn
• Over or less exposure to sunlight
• Viral or bacterial infection
• Medications like beta-blockers, anti-malarial etc.
• Hormonal changes
Following factors can increase the risk of psoriatic arthritis
• Chronic & severe psoriasis
• Psoriasis lesions especially on nails
• Family history
• Adults between the ages of 30 and 50
PsA Development Process – Stage I
This stage is called Accumulation of Toxins stage. The toxins get accumulated at the site of their origin and body tries to get rid of them as and when possible. At stage 1 of toxins accumulation, there is no difference between psoriasis, PsA or any other AI disorder. Although the body is facing regular attack of stress but since immunity system is strong and stress is limited, there is no visible signs of psoriasis.
Our body does provide symptoms of toxins accumulation in the form of Indigestion, Constipation, Acidity, Excessive or Loss of Appetite, Burning Sensation etc.
PsA Development Process – Stage II
Once toxins level is increased or the formation becomes more regular and or blockage of waste disposal tunnels become acute, the stress on the system increases and toxins mix with blood and travel to other body parts. This is called Expansion Stage. Although there is no difference between psoriasis, PsA or any other AI disorder, but constant attack on blood, skin, bone and bone marrow weakens the protective systems and immunity levels.
At this stage our body provides the symptoms in the form of Allergic Reactions, Itching, and Dryness of Skin, Urticaria &/or Eczema.
PsA Development Process – Stage III
With the constant flow of toxins and our body’s inability to coupe with excessive pressure, toxins start accumulating in skin, bone marrow and bone itself. This is called Localization stage.
At this stage the T cells start malfunctioning and start miscommunication.
Bouts of itching and or Urticaria, Eczema, Acute Dryness, break of skin at knee, elbow appear at regular intervals.
Depending on the body profile of the patient, the localization will be skin and or bone.
Only patients with acute localization at bone, synovium, and joint cavity are at the risk of developing full Blown PsA.
This stage of PsA development is just like dynamite is activated but waiting for a trigger to detonate.
PsA Development Process – IV
This stage of development process is called Appearance. After Stage III, the condition is fully developed in the body and waiting for a trigger. Any trigger will make psoriasis appear on the skin.
Generally appearance follows following order but this order can change depending on body profile of patient, accumulation level at skin, bone marrow, bone, joint cavity etc., the trigger and its attacking region:
• Lesions on elbow, knee, scalp, stomach, back etc.
• Severe and full body psoriasis
• Nail pitting and nail deformation
• Joint inflammation and PsA
• Bone deformation
• Permanent disability
Since nails are the excreta of bone, nail pitting and nail deforming precede PsA in 85% of the PsA cases.
In some cases PsA can be developed without developing severe psoriasis or even nail pitting.
For example sports personnel are at greater risk of developing psoriatic arthritis without nail pitting or severe body psoriasis due to regular knee and other joint injuries during sports activities.